By Hoffman-La Roche

What is this medication for?

Ceftriaxone is an antibiotic that belongs to the family of medications known as cephalosporins. It is used to treat infections caused by certain kinds of bacteria. It helps to kill or control the growth of bacteria that may cause gonorrhea, pelvic inflammatory disease, or infections of the lung, urinary tract, skin, abdomen, bone and joints, ear, and lining of the brain. Ceftriaxone may also be used to prevent certain infections.

Your doctor may have suggested this medication for conditions other than those listed here. As well, some forms of this medication may not be used for all of the conditions discussed here. If you are not sure why you are using this medication, speak to your doctor. Do not stop using this medication without consulting your doctor.

Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to use this medication if their doctor has not prescribed it.

What form(s) does this medication come in?

Rocephin® is available as:

  • injection
    • 500 mg per vial
    • 1 g per vial
Some medications may have other generic brands available. Always ask your doctor or pharmacist about the safety of switching between brands of the same medication.

How should I use this medication?

The recommended dose and dosing schedule of ceftriaxone varies according to the specific infection being treated, the response to therapy, and other medications or treatments being used.

Adult doses range from 1 g to 4 g given once every 12 to 24 hours.

Pediatric doses are based on weight.

Ceftriaxone is injected into a vein or into a muscle by a health care professional under the supervision of your doctor. Treatment may be necessary for a matter of days to weeks, depending on the infection being treated.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are using the medication without consulting your doctor.

Keep this medication out of the reach of children.

Who should NOT take this medication?

Ceftriaxone should not be taken by anyone who:

  • is allergic to ceftriaxone or to any ingredients of the medication
  • is allergic to any of the cephalosporin antibiotics (e.g., cephalexin, cefazolin)

If you are allergic to penicillin, check with your doctor before taking ceftriaxone as some people who are allergic to penicillin are also allergic to cephalosporin antibiotics such as ceftriaxone.

Ceftriaxone should not be given to newborns at the same time as products containing calcium, or to newborns with hyperbilirubinemia (high blood levels of bilirubin).

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Reviewer: Brittany Mills
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